Background: The magnitude and risk factors of progression of atherosclerosis in Asian HIV-infected individuals were unknown.

We aimed to elucidate the incidence of NADCs and its predictive factors in Asian HIV-infected patients.

Conclusions: Asian HIV-infected individuals had atherosclerosis progression.

Limb fat percentage, LDL cholesterol particle size, and adiponectin level may identify at-risk Asian HIV-infected individuals for early intervention.