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1 Results suggest that communal coping predicts better abstinence outcomes in couple-based AUD treatment .
2 Clinicians and researchers should assess opioid misuse and other drug use in patients undergoing AUD treatment .
3 Future work examining heterogeneity in mediators and outcomes may help refine AUD treatment to be maximally effective.
4 Conclusions: Opioid misuse and other drug use were associated with poorer AUD treatment outcomes, which was partially mediated by medication adherence.
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