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The Shigella bacteria cause bacillarydysentery, which remains a significant threat to public health.
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The intracellular pathogen Shigella flexneri is the causative agent of bacillarydysentery in humans.
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Here we outline advances provided by a recently developed infant rabbit model of bacillarydysentery.
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The isolation of S. dysenteriae-1 remains the preferred test for the diagnosis of bacillarydysentery.
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The bacterial pathogen Shigella flexneri causes more than 250 million cases of bacillarydysentery (blood in stool) every year across the world.
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A major challenge in combating bacillarydysentery is the lack of a small-animal model that recapitulates the symptoms observed in infected individuals, including bloody diarrhea.
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The bacterial pathogen Shigella flexneri causes 270 million cases of bacillarydysentery (blood in stool) worldwide every year, resulting in more than 200,000 deaths.