Meanings of cause mutations in English

DNA damage can cause mutations that contribute to cellular transformation and tumorigenesis.

The resulting uracils cause mutations and strand breaks that inactivate viruses and diversify antibody repertoire.

Therefore, the para adduct may adopt multiple orientations in DNA helices and potentially cause mutations by forming pairs with different natural bases.

As a consequence, these insertions provide a source of genetic variation and, in rare cases, these events cause mutations that lead to disease.

Search for causing mutations is very laborious, time consuming and low effective.

These insights from yeast relate directly to disease- causing mutations in human septins.

Spontaneous reversion of disease- causing mutations has been observed in some genetic disorders.

But it can take weeks to identify drugs targeting cancer- causing mutations.

The Hour of God's Eye has caused mutations in every species.

We have examined the molecular basis for three such cancer- causing mutations.

Most human transcripts are alternatively spliced, and many disease- causing mutations affect RNA splicing.

Also considered as potential disease- causing mutations (DCMs) were 27 rare additional mutations.

Overall, only nine genes showed strong evidence for disease- causing mutations.

Understanding these mechanisms provides insights into the vulnerabilities of these receptors to disease- causing mutations.

A significant clustering of the missense disease- causing mutations was found at the domain-domain interfaces.

This hydrophobic gating mechanism has implications for CRAC channel function, pharmacology and disease- causing mutations.