Meanings of central ulceration in English

In one patient, capsular retraction was associated with central ulceration extending to and eroding the liver capsule.

In 1992, a 59-year-old women developed a hard dorsal lesion with central ulceration and scar formation requiring excision and graft.

A 13-year-old girl presenting with severe anemia was diagnosed to have a large gastric tumor protruding toward the antrum with two central ulcerations.