Who are the chief instigators to what you call vice and folly?

The fatty acids carried on albumin may be the chief instigators of tubulointerstitial injury in protein-overload proteinuria.

The coach said it would be impossible to work in a hostile environment and pegged Ultras as the chief instigators.

It was from a report written by the Reverend Samuel Parris, who was one of the chief instigators of the witch-hunt.

Mac Diarmada was one of the seven signatories of the Proclamation and, along with Tom Clarke, one of the chief instigators of the Rising.

(The scholars, clergy, and officials were subjectively the chief instigators of plunder, but objectively they were merely the medium of plunder.)