1
In the chronic DSS colitis model SBA treatment significantly reduced clinical symptoms in a dose-dependent manner.
2
ROCK inhibition reversed established fibrosis in a chronic DSS model and impeded ex vivo pro-fibrotic protein secretion from stenotic CD biopsies.
3
No beneficial effects were observed if HO-1 was induced by CoPP after the onset of acute colitis or in chronic DSS-induced colitis.