1
The low rate of physician refusal acknowledges clinical equipoise in the study design.
2
Conveying clinical equipoise and exploring patient treatment preferences can enhance recruitment and patient understanding.
3
The balance between benefits and harms of SUP is unknown, and clinical equipoise exists.
4
Does clinical equipoise apply to CRTs?
5
Misunderstanding of clinical equipoise was prevalent.
6
Current guidelines reflect a shift toward early surgery for such patients, but there continue to be important areas of clinical equipoise.
7
We had defined, discussed and illustrated the principle of clinical equipoise that ethically and methodologically justifies the randomisation in clinical trials.