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A small coagulationdefect at the site of the former lesion was the only morphological change.
2
Successful therapy required an individualized approach, employing multiple replacement strategies, based on the laboratory definition of the specific additional coagulationdefect.
3
Mutations in a candidate gene in this region, ERGIC-53, were recently found to be associated with the coagulationdefect in nine Jewish families.
4
VHF is characterized by fever, vascular leakage, coagulationdefects and multi organ system failure.