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1
These data indicate that cargo packaging into COPI-
coated
vesicles
requires hydrolysis of GTP.
2
Coated
vesicles
are thought to be vehicles for the intracellular transport of membranes.
3
The formation of COPII-
coated
vesicles
is regulated by the GTPase cycle of Sar1.
4
Clathrin-
coated
vesicles
were the first discovered and remain the most extensively characterized transport vesicles.
5
Clathrin-
coated
vesicles
mediate trafficking of proteins and nutrients in the cell and between organelles.
6
Electron microscopy analyses revealed albumin-gold complexes localized in caveolae, but not in clathrin-
coated
vesicles
.
7
Clathrin is the major protein component of
coated
vesicles
.
8
Coated
vesicles
concentrate and package cargo molecules to mediate their efficient transport between intracellular compartments.
9
Coated
vesicles
may be involved in removing these aggregates.
10
A concerted conformational change would then close the rings and pinch off the budding
coated
vesicles
.
11
The transition to the vitellogenic stages is marked by the accumulation of yolk via clathrin-
coated
vesicles
.
12
An affinity-purified tubulin antiserum can precipitate
coated
vesicles
.
13
Coated
vesicles
are involved in the intracellular transport of membrane proteins between a variety of membrane compartments.
14
An immunoadsorption technique could therefore be used to fractionate
coated
vesicles
on the basis of their membrane composition.
15
A presumable functional role of both protrusions and membrane-
coated
vesicles
in pathogenicity of different sarcosporidian species is proposed.
16
Phosphoinositides serve as key membrane determinants for assembly of clathrin coat proteins that drive formation of clathrin-
coated
vesicles
.