Meanings of conditional knockout in English

To further examine lincRNA-p21 function, we generated a conditional knockout mouse model.

DCAF2 DC- conditional knockout mice displayed increased sensitivity to autoimmune diseases.

Therefore, the conditional knockout mouse is an invaluable platform.

In this study, we used NS-Pten conditional knockout mice (a well-studied genetic model of epilepsy).

Because of systemic 5-HT deficiency, conditional knockout of Piezo1 increased bone formation.

To test the physiological significance of this interaction, we generated conditional knockout mice lacking all multidomain RIM isoforms.

A role for e-cadherin was also assessed using a unique conditional knockout of e-cadherin in adult mouse esophagus.

Their elevated plasma LDL levels are lowered after conditional knockout of the gene encoding microsomal triglyceride transfer protein.

To address this question, we produced triple cKO ( conditional knockout) mice that allow ablating all neurexin expression in mice.

We used conditional knockout mice to study the impact of reducing glucose transport across the RPE on photoreceptor and Müller glial cells.

The conditional knockout of HS from keratocytes using the keratocan promoter led to no corneal abnormalities or any disruption in wound healing.

In this study, we showed that Arid1a conditional knockout mice had a high incidence of SCCs occurring in the tongue and esophagus.

Purpose: Based on the Cre-Loxp gene knockout system, this study intended to construct tamoxifen-inducible STAT3 conditional knockout mice and verify the knockout efficiency.

By generating LC-ASL- conditional knockout (cKO) mice, we further demonstrate altered response to stressful stimuli with increased seizure reactivity in LC-ASL-cKO mice.

Using conditional knockout mice, we found that myeloid Hdac3 deficiency promotes collagen deposition in atherosclerotic lesions and thus induces a stable plaque phenotype.

We have generated a conditional knockout model of p120ctn whereby mice develop preneoplastic and neoplastic lesions in the oral cavity, esophagus, and squamous forestomach.