Meanings of conditional ko in English

In this study, we generated neural progenitor cell-specific Pen-2 conditional KO mice.

Using the classical conditional KO approach, reseachers can avoid embryonic lethality, but they cannot modulate genes in a temporally controllable way.

To address this question, we generated a conditional KO (cKO) mouse in which Pen-2 is specifically inactivated in neural progenitor cells in the telencephalon.