Meanings of conformational entropy in English

Initial results reveal a large and variable role for conformational entropy in the binding of ligands by proteins.

Such a role for conformational entropy in molecular recognition has significant implications for enzymology, signal transduction, allosteric regulation and the development of protein-directed pharmaceuticals.

One of the most difficult contributions to the free energy of protein-ligand complexes to access experimentally is that due to changes in protein conformational entropy.