1
TG hearts exhibited improved recovery of contractile performance over the whole reperfusion period.
2
Mitochondria are highly abundant in and essential to the beat-to-beat contractile performance of hearts.
3
In athletes, an increase in left atrial volumes is observed, associated with decreased atrial contractile performance and enhanced conduit function.
4
Functional and structural measurements validated improved myocardial contractile performance, reduced ventricular size and decreased cardiac damage in the treated cohort.
5
Conclusions: HEP are preserved over a wide range of contractile performance in the donor heart, with no metabolic difference between the two ventricles.
6
Strikingly, GRK2 ablation initiated 10 days after infarction increased survival, enhanced cardiac contractile performance, and halted ventricular remodeling.
7
Obesity-related impairment of endothelium-dependent relaxation of the aorta was markedly attenuated by temporary periaortic fat removal whereas obesity-related enhancement of contractile performance was unaffected.
8
Overall, our data indicate that S100A1 gene therapy provides a potential novel treatment strategy to maintain contractile performance of the post-MI heart.