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Huntington's disease is characterized by highly selective and profound damage to the corpusstriatum, which regulates motor function.
2
RNase protection assay revealed about a 1.5-fold increase in the D2 dopamine receptor mRNA level in the corpusstriatum.
3
At E15-E19, the majority of cells in the plate stain, with their processes extending through the corpusstriatum to the thalamus.
4
Medium sized-spiny neurons (MSNs) in the corpusstriatum are highly vulnerable to mHtt aggregate accumulation and degeneration, but the mechanisms and pathways involved remain elusive.