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Exclusion criterion was the administration of cytostaticagents prior to diagnosis.
2
The response level was significantly lower in cases of monotherapy when compared to combinations of cytostaticagents.
3
Manipulating the autophagy lysosomal pathway in cells treated with cytostaticagents can promote apoptotic cell death in some cases.
4
During the initial 15 weeks adriamycin was used preferentially and cytostaticagents were applied in a higher frequency than later on.
5
Cardiotoxicity of cytostaticagents is a very serious side effect of anti-cancer therapy, which may affect survival more than the malignancy itself.
6
It can develop in previously irradiated areas and has been shown to be triggered by a variety of different drugs, including cytostaticagents.
7
Therefore, cytostaticagents that cause arrest of the cell cycle in the S-phase may initially increase FLT uptake rather than reducing the tumour cell accumulation.