Meanings of dedifferentiate in English

Soon after amputation, cardiomyocytes dedifferentiate and proliferate to regenerate the missing tissue.

There are no animal scleroderma esophagus models and esophageal smooth muscle cells dedifferentiate in culture prohibiting in vitro studies.

In other words, a skin cell can dedifferentiate into a stem cell, then regenerate into a muscle cell or another completely different type of cell.

In this case, magnetic resonance imaging was useful in diagnosing dedifferentiated chondrosarcoma before surgery.

Fifty cases were retrieved, reviewed and FNCLCC grade was scored for the dedifferentiated component.

T2-weighted imaging was used to distinguish between the cartilaginous component and the dedifferentiated one.

Epithelial glandular differentiation in dedifferentiated chondrosarcoma has not been described.

However, the molecular identity of the differentiated and dedifferentiated states in vivo has been elusive.

Going back to the spermatazoa method they mentioned, they could be talking about dedifferentiating your sperm.

In vitro dedifferentiated plant cell cultures are a useful tool for the study of molecular processes.

While some cells are dedifferentiating, others have already begun regenerating and differentiating, or becoming specialized cells.

We conclude that ERalpha activation switched SMC to a dedifferentiated phenotype and may contribute to plaque instability.

Immunohistochemical staining revealed strong expression of vascular endothelial growth factor in the tumor cells in the dedifferentiated component.

In well-differentiated and dedifferentiated liposarcoma their clinical promise is associated with their ability to downregulate the MDM2 protein.

Both peripheral and central dedifferentiated chondrosarcomas are high-grade malignant lesions and require wide or radical surgical margins for adequate treatment.

MDM2 amplification level remains a useful diagnostic tool in dedifferentiated liposarcoma, but has no prognostic value in terms of local recurrence.