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No studies have underpinned the nexus between induction of demodicosis and neural immunosuppressive pathways so far.
2
Simultaneously, remarkable reduction in circulatory pro-inflammatory cytokine tumour necrosis factor-alpha level was observed in dogs with demodicosis.
3
The exact pathogenesis of canine demodicosis is unknown but an aberration in immune status is considered very significant.
4
It is concluded that premature apoptosis of PBL may be implicated in the immunosuppression of the dogs with demodicosis.
5
The aim of the present study was to evaluate the status of apoptosis in peripheral blood leukocytes of dogs with demodicosis.