1 Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV .
2 In the Caribbean, DENV is also epidemic and responsible for severe thrombocytopenia.
3 These studies establish a role for nutritional status in DENV disease severity.
4 These results reflect our recent findings in a mouse model of DENV cross-protection.
5 No behavioral or demographic factors were significantly associated with DENV infection.
6 The mechanism by which DENV infects the host cell remains unclear.
7 Here we review the strategies to identify inhibitors for DENV therapy.
8 We show that immature DENV is infectious in cells expressing DC-SIGN.
9 Neither vaccine nor effective therapeutics is currently available for DENV .
10 Skin immune cells are an important component of initial DENV infection and systemic spread.
11 To date, no vaccines or antiviral therapeutics have been approved for combating DENV - associated disease.
12 Dengue virus ( DENV ) is the most common arthropod-borne viral disease of humans.
13 Overall, the cross-reactive B cell immune response dominates during secondary DENV infections in humans.
14 Conclusions: Southeast Asia countries were found to be the possible source of DENV in Guangzhou.
15 Therefore, we carried out a comprehensive investigation into the molecular characteristics of the DENV - 3 involved.
16 Interestingly, DENV strains from different years had different origins.
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