1
Endothelium- derived nitric oxide plays a major role in the regulation of vascular tone and in the maintenance of vascular homeostasis.
2
Diminished release and function of endothelium- derived nitric oxide coupled with increases in reactive oxygen species production is critical in endothelial dysfunction.
3
Conclusions: Collectively, the authors' results showed that high-dose morphine impairs vascular endothelial function via attenuation of biologic activity of endothelium- derived nitric oxide.
4
These results suggest that sepiapterin inhibits uncoupling of NOS and improves LV function presumably by increasing iNOS- derived nitric oxide in the diabetic heart.
5
The reduced bioavailability of endothelium- derived nitric oxide may play a role in endothelial vasodilator dysfunction and thus in the structural changes characterizing CAV.
6
In the vasculature of rodents, SIRT1 mediates vasodilatation through the release of endothelial nitric oxide synthase- derived nitric oxide and scavenges reactive oxygen species.
7
Background: Digital pulse amplitude augmentation in response to hyperemia is a novel measure of peripheral vasodilator function that depends partially on endothelium- derived nitric oxide.
8
Objective: The aim was to assess the importance of endothelium derived nitric oxide (NO) in the regulation of vascular tone in the limbs.
9
Administration of hemoglobin-based oxygen carriers (HBOCs) frequently results in vasoconstriction that is primarily attributed to the scavenging of endothelium- derived nitric oxide (NO) by cell-free hemoglobin.