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The mdx diaphragmmuscle closely mimics the pathophysiological changes in DMD muscles.
2
Controlled mechanical ventilation induced a profound diaphragmmuscle dysfunction and atrophy.
3
The time- and dose-dependent effects of acute high-dose corticosteroids on the diaphragmmuscle are poorly defined.
4
Thus, pharmacological inhibition of the RyR1 in diaphragmmuscle fibers is not sufficient to prevent MV-induced diaphragm atrophy.
5
The mdx diaphragmmuscle most closely recapitulates key features of DMD muscles, including progressive fibrosis and considerable force loss.
6
Improved detection of diaphragm atrophy is essential for clinical practice and for management of trials specifically targeting diaphragmmuscle function.
7
Tongue and diaphragmmuscle samples were collected from 728 pigs and tested for Trichinella larvae by the artificial digestion method.
8
However, prolonged MV causes the rapid development of diaphragmmuscle atrophy, and diaphragmatic weakness may contribute to difficult weaning from MV.
9
At the end of the experiment, mitochondrial ROS emission, protease activation, and fiber cross-sectional area were determined in diaphragmmuscle fibers.
10
Overall, the murine model of PH elicited by MCT mimics loss of body weight and diaphragmmuscle weakness reported in PH patients.
11
However, it is unclear if PH induced by MCT in mice reproduces the loss of body weight and diaphragmmuscle dysfunction seen in patients.
12
Methods: Costal diaphragmmuscle biopsies were acquired from 13 patients with moderate and severe COPD and 8 control subjects.
13
All diaphragmmuscle fiber types were significantly atrophied in C-26 mice compared to controls, and the atrophy-related genes, atrogin-1 and MuRF1, significantly increased.
14
Thus, the purpose of the current study was to determine whether colon-26 (C-26) cancer cachexia causes diaphragmmuscle fiber atrophy and weakness and compromises ventilation.
15
Fibrocytes were detected in acutely injured muscles and in mdx5cv quadriceps and diaphragmmuscles.
16
He stood with his diaphragmmuscles tense and paralyzed, making convulsive efforts to breathe.