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1 In contrast, in PD and DLB cases there is abnormal accumulation of alpha-synuclein in neuronal cell bodies, axons, and synapses.
2 The cohort comprised 788 DLB cases and 2624 controls.
3 Here, we used whole-genome genotyping of 1454 DLB cases and 1525 controls to assess copy number variability.
4 To minimize the issue of potential misdiagnosis, we have also performed the analysis including only neuropathologically proven DLB cases (667 cases).
5 All of the DLB cases had neuropathologic evidence of AD sufficient to meet CERAD criteria for a diagnosis of definite AD plus nigral Lewy bodies.
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