1
Androgens, produced by the embryonic testis, have been shown to be crucial to this process.
2
To understand the potential actions of TGF-alpha in the embryonic testis, general cell proliferation was investigated.
3
Treatment of embryonic testis organ cultures with exogenous TGF-alpha also perturbed development, leading to an increased proliferation of unorganized cells.
4
The current study was an investigation of the hypothesis that transforming growth factor-alpha (TGF-alpha) is involved in regulating embryonic testis growth.
5
Embryonic testis development requires the morphogenesis of cords and growth of all cell populations to allow organ formation.