Meanings of endogenous inhibitor in English

These data suggest that endostatin may be an endogenous inhibitor of vasopermeability as well as neovascularization.

SclAb increases bone mass by suppressing the action of the endogenous inhibitor of bone formation, Scl.

In conclusion, our data demonstrate that lactate at physiologically relevant concentrations is a potent endogenous inhibitor of TRPV1.

These findings are in accordance with previous in vitro studies showing that caveolin-1 is an endogenous inhibitor of eNOS.

The mechanisms of proteasome inhibition could involve the formation of an endogenous inhibitor such as protein aggregates or aldehyde-derivative peptides.

Purified PICOT protein inhibited the kinase activity of PKCζ in vitro, which indicated that PICOT is an endogenous inhibitor of PKCζ.

Collectively, our results demonstrate that FKBP12 forms an endogenous inhibitor of EGFR phosphorylation directly involved in the control of cellular EGFR activity.

Several lines of evidence have implicated activated protein C (APC) to be an endogenous inhibitor of the inflammatory septic cascade.

We propose that the heme moiety through its coordination with His-105 of the beta subunit acts as an endogenous inhibitor of sGC.

MCJ (also known as DnaJC15) is a mitochondrial inner membrane protein identified as an endogenous inhibitor of respiratory chain complex I.

To circumvent this adverse side effect, we chose to modulate GK activity by targeting the endogenous inhibitor of GK, glucokinase regulatory protein (GKRP).

In hepatocytes, GK regulates glucose uptake and glycogen synthesis, suppresses glucose production, and is subject to the endogenous inhibitor GK regulatory protein (GKRP).

RCAN1.4 is best characterized as an endogenous inhibitor of the phosphatase calcineurin, and it has been observed to be downregulated in numerous types of cancer.

The NO generation by these cells is also regulated by some endogenous inhibitors, like TGF-beta.

TKase activity was not restored by removal of endogenous inhibitors but was restored by treatment with uridine.

The biologic relevance of endogenous inhibitors of angiogenesis in the control of hair cycling, however, has remained unknown.