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This method should be useful in molecular epidemiological studies investigating relationships between the susceptibility from environmentalcarcinogen exposure and cancer risk.
2
DPCs can be induced endogenously or through environmentalcarcinogens and chemotherapeutic agents.
3
Genetic alterations in cancer tissues may reflect the mutational fingerprint of environmentalcarcinogens.
4
Asbestos, like many environmentalcarcinogens, has a long latency period.
5
These techniques are particularly useful for screening human populations for exposure to potential environmentalcarcinogens.
6
Environmentalcarcinogens, in a strict sense, include outdoor and indoor air pollutants, as well as soil and drinking water contaminants.
7
Results demonstrate that cumulative exposures to multiple environmentalcarcinogens and neurotoxins can be comparatively high for children from a poor inner-city neighborhood.
8
Conclusions: These results point toward a role of AGT polymorphisms in lung cancer susceptibility among never-smokers, in particular among subjects exposed to environmentalcarcinogens.
9
Current knowledge is insufficient to explain why only a proportion of individuals exposed to environmentalcarcinogens or carrying a genetic predisposition to cancer develop disease.