Using epigenetic signatures, we identified enhancers for each developmental stage.

Conclusions: Early childhood malnutrition entails long-lasting epigenetic signatures associated with liability for attention and cognition, and limited potential for intergenerational transmission.

In this respect, we propose the assessment of epigenetic signatures in the brainstem as the cornerstone of interrogating causality in AD.

This choice of parent cells was supposed to enhance limbal cell differentiation from iPSCs by partial retention of parental epigenetic signatures in iPSCs.