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In this study, we have shown that these cells bound 125I-epo specifically.
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The researchers used three groups of mice to test the effect of epo.
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Neither cell lines respond to epo to differentiate.
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Anyone who follows cycling knows about epo.
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Binding could be displaced by the presence of unlabeled epo but not by insulin or epidermal growth factor.
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Some received no treatment, some were injected with human epo, and some were genetically modified to produce human epo in the brain.
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It is suggested that the absence of "high" affinity receptors may account for the lack of responsiveness of these cells to epo.
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When used in repeated small dosages as a performance-enhancing drug, kidney-derived epo stimulates the production of red blood cells, enhancing oxygen delivery and utilization.
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Compared to the mice that received no additional epo, the doped mice showed significantly higher running performance without the damaging increase in red blood cells.
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What's more, it did so without causing the erythropoiesis, or elevated red blood cell counts, that typically occurs when epo is used to boost performance.
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If brain epo makes you want to do it, without actually building the blood cells, we can now look for similar things that aren't harmful.
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The epos is the calm quiet representation of an action in progress.
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Baseline serum EPO levels were similar for patients with and without PTE.
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EPO use thickens the blood and increases the risk of heart attacks.
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We hypothesized that a link between resistin and EPO responsiveness may exist.
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Some estimate that for every EPO user discovered, 10 others get away.