1
The prostate was co-registered using a free-form deformation (FFD) algorithm based on B-splines.
2
In the fine registration, a local B-spline FFD model with normalized mutual information gradient is employed.
3
The experimental results show that our algorithm is more accurate than the hierarchical local B-spline FFD method.
4
Further, the modified Hausdorff-distance was no different between demons modes 1 and 2, but mode 1 was 15.2% lower than FFD.
5
The average NMI after demons registration method in mode 1 improved 1.76% and 4.75% when compared to mode 2 and FFD model algorithm, respectively.