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Meanings of feel a gnaw in English

We have no meanings for "feel a gnaw" in our records yet.
Usage of feel a gnaw in English
1
He felt a gnaw of disappointment.
Speaks the Nightbird
2
Heat's gaze came to rest on the yawning Hastings-to-Henderson drawer, the one where her file would have resided-andfelt a gnaw.
Driving Heat
3
Although he had breakfasted only two hours before, he felt a gnawing hunger, as if he had not eaten anything for several days.
From the Earth to the Moon; and, Round the Moon
4
Before that, he had lived as others live, content to avoid deadly sin; but all the time he had felt a gnawing reproach within him.
Christian Mysticism