1
The formation of this protein network shares features with amyloid fibril formation.
2
The tetrapeptide KFFE is one of the shortest amyloid fibril-forming peptides described.
3
The model thus provides a generic picture of hierarchical fibril formation.
4
The rate of fibril formation was highly dependent on the initial protein concentration.
5
Diagnosis requires demonstration of amyloid deposition and confirmation of the fibril protein type.
6
Paraspinal muscle tissues of AS patients exhibited increased collagen fibril accumulation and atrophy.
7
Oligomers are commonly observed intermediates at the initial stages of amyloid fibril formation.
8
Chelerythrine showed inhibition of fibril formation in the same range as propidium iodide.
9
Amyloid fibril formation is associated with a number of debilitating systemic and neurodegenerative diseases.
10
There was no clear correlation between the rate of fibril elongation and ionic strength.
11
Our multiscale approach may be used for other fibril-forming peptides.
12
The Silver protein is required for intralumenal fibril formation in melanosomes by amylogenic cleavage.
13
Additional methods for strain comparison were utilized including lesion profiles, fibril stability, and western blotting.
14
Albumin-Aβ binding is important in preventing Aβ fibril aggregation.
15
The results indicate that low concentrations of some metals can directly induce alpha-synuclein fibril formation.
16
Using electron microscopy abundant collagen fibril formation was shown.
