Meanings of functional annotation in English

Summary: SNPnexus database provides functional annotation for both novel and public SNPs.

Our results provide a strategy for functional annotation of the human miRnome.

Nevertheless, genomic sequence information is missing and functional annotation of transcripts and proteins is limited.

Analyses of interdomain interactions and provisional functional annotation of the remaining, so-far-uncharacterized domains are presented.

Using functional annotation, we were able to identify several rare nonsynonymous variants that were enriched in each family.

The atlas provides a resource for the functional annotation of genes that currently have only a locus ID.

Next, we provide a comparative functional annotation of the sheep genome, validated using experimental ChIP-Seq of sheep tissue.

Further functional annotation demonstrated that the differentially expressed genes were mainly involved in cell cycle and cancer progression.

These data were used to explore the functional annotation of 45,187 fully annotated contigs.

Biological functions, pathways, and regulators enriched for differentially expressed genes or module members were identified through functional annotation analyses.

In this context, the identification of protein domains is a key step to improve the functional annotation of the proteins.

In recent years, multiple types of high-throughput functional genomic data that facilitate rapid functional annotation of sequenced genomes have become available.

Conclusions: DNA microarrays based on long oligonucleotides are powerful tools for the functional annotation and exploration of the P. falciparum genome.

Thus, it facilitates the analysis of complex ISH gene expression patterns, as well as functional annotation and interaction of gene sets.

Correspondence analysis and functional annotation analysis indicated that the spectral index improves the identification of enriched proteins corresponding to clinical phenotypes.

The identification of regulatory regions is one of the most important and challenging problems toward the functional annotation of the human genome.