Meanings of gated sodium in English

Both compounds have been reported to modulate voltage- gated sodium channel activity.

Tetrodotoxin is a low molecular weight compound that acts by blocking voltage- gated sodium channels, inducing paralysis.

However, how voltage- gated sodium channels impose a pro-metastatic behavior to cancer cells is much less documented.

Specific peptide toxins interact with voltage- gated sodium channels by regulating the activation or inactivation of targeted channels.

Voltage- gated sodium (NaV) channels are essential for initiating and propagating action potentials in the brain.

The persistent current (INaP) through voltage- gated sodium channels enhances neuronal excitability by causing prolonged depolarization of membranes.

Knockdown resistance mutations, specifically F1534C, in the voltage- gated sodium channel gene, and increased activity of detoxifying enzymes were evaluated.

The present study focused on those voltage- gated sodium channels, which are the structural basis for generation of ectopic action potentials.

Specifically, the gympietides interfere with an important pathway for conducting pain signals in the body, called voltage- gated sodium ion channels.

ST-2530 exhibited greater than 500-fold selectivity over human voltage gated sodium channel isoforms Nav1.1-Nav1.6 and Nav1.8.

Voltage- gated sodium channels (Na V s) are activated by transiting the voltage sensor from the deactivated to the activated state.

This article describes the effect of the pyrethroid insecticide deltamethrin on the cardiac voltage- gated sodium channel Nav1.5.

Voltage- gated sodium channels are involved in tumor metastasis, as potentiating or attenuating their activities affects the migration and invasion process of tumor cells.

Identification of voltage- gated sodium channel NaV1.7 inhibitors for chronic pain therapeutic development is an area of vigorous pursuit.

The nervous system maintains a delicate balance between excitation and inhibition, partly through the complex interplay between voltage- gated sodium and potassium ion channels.

However, it has become increasingly clear that treatment strategies targeting voltage- gated sodium or calcium channels merely mask the symptoms of epilepsy without providing disease-modifying benefits.