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What is less clear is how these changes interact with trans-acting changes occurring elsewhere in the geneticcircuit.
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In a normal cell, powerful geneticcircuits regulate cell division and cell death.
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We found 364 candidate obesity-regulating cis elements and geneticcircuits in different cell types.
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Cells act like tiny computers, and finally, scientists are figuring out what makes their geneticcircuits blink on and off.
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This finding leads to the proposal that mathematicians study geneticcircuits to find new geometries for which structure theorems may exist.
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Now that they've gotten these basic geneticcircuits to work, the next step is to make the logic gates work in different types of cells.
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A combined analysis of these functional and regulatory ILP interactions identifies local geneticcircuits that act in parallel and interact by crosstalk, feedback and compensation.