This becomes a source of great annoyance and loss to the breeder.

Many tribes of Indians and travellers suffer great annoyance from the vampire-bats.

When grown up it is a source of great annoyance and shame.

A brother like this was a great annoyance to Madame de Maintenon.

This clause should be jealously inspected, otherwise great annoyance may be produced.

Donna Tullia hesitated a moment, and then accepted, to Orsino's great annoyance.

�Won�titbe a great annoyance to you, Mrs. Sampson? �sheasked.

To his great annoyance, he had to be down in Mexico that day.

They overran the White House and gave the President great annoyance.

But to his great annoyance she was not alone; Nellie was with her.

And then, after the Prussian war there is no further great annoyance possible.

Under this pretense they stopped three days, feigning great annoyance at the delay.

These people with their complaints and their comments were causing him great annoyance.

Then the signers risked certainly great annoyance, sometimes imprisonment, and not infrequently death.

One of them gave him great annoyance, and he inquired for its author.

They are a great annoyance, and have defoliated whole vineyards here last fall.