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Meanings of great mutations in English

We have no meanings for "great mutations" in our records yet.
Usage of great mutations in English
1
No geologist disputes that great mutations of level have occurred within the period of existing organisms.
The Origin of Species by Means of Natural Selection / Or, the Pr...
2
All great mutations shake and disorder a state.
Essays of Michel de Montaigne — Volume 17
3
The great mutations of the world are acted, or time may be too short for our designes.
The Guardian
4
The great mutations of the world are acted, or time may be too short for our designs.
Religio Medici, Hydriotaphia, and the Letter to a Friend
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