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Growth impairment of stroma and haemopoietic precursors persisted for 10 and more years after IS.
2
The haemopoietic reconstitution was significantly delayed in 3 patients.
3
It may provide a direct evidence that the B lymphocyte also possesses some haemopoietic modulation effects.
4
In recent years we have done a series of observations on the haemopoietic modulation effects of lymphocytes.
5
We report an analysis of 13 children transplanted using an HLA-partially matched donor as source of haemopoietic stem cells.
6
However, when bone marrow support with haemopoietic growth factors was used to allow paclitaxel dose intensification, neurotoxicity became dose limiting.
7
These results suggest that the proteolytically activated and phospholipid-independent form of PK-C is probably not involved in haemopoietic cell differentiation.
8
The dose-response curves of serum samples from healthy volunteers and patients with haemopoietic disorders were parallel to the standard curves.
9
Following a pilot study, an internet-based questionnaire was distributed to individuals in key research positions in the European haemopoietic SCT community.
10
To define regulatory elements of the mouse GATA-1 gene, we mapped DNaseI-hypersensitive sites in nuclei of erythroid and haemopoietic progenitor cells.
11
These findings suggest that the different dose rates and fractionation used in this study caused similar radiation damage to the murine haemopoietic system.
12
Both haemopoietic stem cell transplantation and enzyme replacement therapy can be applied to the treatment of the disorder; however, they both present several limitations.
13
Over-expression of the c-myb gene and expression of activated forms of myb are known to transform haemopoietic cells, particularly cells of the myeloid lineage.
14
In an attempt to ameliorate these limitations, umbilical cord blood has been postulated as an alternative source of allogeneic haemopoietic stem cells for transplantation.
15
Murine retroviruses which encode c-myb proteins that have either complete or truncated carboxy (C) termini were used to infect haemopoietic cells from murine fetal liver.
16
These findings suggest that the cell of origin of secondary AML and ALL with 11q23 rearrangement is an immature haemopoietic progenitor cell.