Meanings of hallmark feature in English

Its hallmark feature is refractory seizures during the first year of life.

Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes.

Airway remodeling is a hallmark feature of asthma and chronic obstructive pulmonary disease.

Chromosomal translocations involving the immunoglobulin switch region are a hallmark feature of B-cell malignancies.

Background: Action tremor is the hallmark feature of essential tremor (ET).

Action tremor is the hallmark feature of ET.

This suggests that peripheral limitations may play a significant role in HF limiting exercise tolerance, a hallmark feature of HFpEF.

A hallmark feature of Huntington's disease pathology is the atrophy of brain regions including, but not limited to, the striatum.

In addition to hypokalaemic metabolic alkalosis, hypomagnesaemia associated with hypocalciuria is considered to be a hallmark feature of this latter disorder.

This hallmark feature has been reproduced in experimental models, but neither its pathogenesis nor clinically relevant features have been fully elucidated.

A hallmark feature of glioblastoma is its strong self-renewal potential and immature differentiation state, which contributes to its plasticity and therapeutic resistance.

Chronic tissue ischemia due to defective vascular perfusion is a hallmark feature of peripheral artery disease for which minimal therapeutic options exist.

Airway hyperreactivity is a hallmark feature of asthma and can be precipitated by airway insults, such as ozone exposure or viral infection.

A hallmark feature of viral web stories in publications like Buzzfeed has always been the inclusion of a smattering of tweets or Facebook posts.

Background: Reduced prepulse inhibition (PPI) of the auditory startle reflex is a hallmark feature of attention-processing deficits in patients with schizophrenia and other psychotic disorders.

Significance statement: Synaptic dysfunction and cognitive decline are early hallmark features of Alzheimer's disease.