Conclusion: Based on this small sample of patients, it appears that the hearing disorders associated with Fabry disease develop mainly in adulthood.

Multipotent cochlear neural progenitors (CNPs) in the organ of Corti hold the promise for cell replacement in degenerative hearing disorders.

Early diagnosis of thyroid malfunction, hearing disorders and sight problems has also helped improve the quality of life of many children with Down syndrome.

This work develops a new in vitro methodology for the maintenance and self-regeneration of CNPs for future design of regenerative strategies for hearing disorders.