The distribution of HLAs according to disease severity and latency period was assessed.

Outcomes improve with matching at HLAs, but other factors are required to explain residual risk of GVHD.

These results have important implications for the development of a malaria vaccine to protect a population with diverse HLAs.

Human leukocyte antigens (HLAs) play an important role in the regulation of immune response against infectious organisms, including HBV.

Further investigation of the roles of class II HLAs in HIV-1 transmission and as possible components of HIV-1 vaccines should be pursued.