Cell-culture studies using inhibitors of HMG-CoA reductase have suggested an immunosuppressive effect.

Virus encoded homologues of HMG proteins have not been reported so far.

HMG-CoA reductase inhibitors have direct vascular effects that contribute to plaque stability.

This regulation is rapid and coordinate with that observed for HMG-CoA reductase.

The Prism is the first HMG pack to get a traditional brain.