Meanings of human monoclonal in English

This approach led to the mapping of two broadly neutralizing human monoclonal antibodies with conformation-dependent epitopes.

Denosumab is a human monoclonal antibody which inhibits RANKL and impairs the growth of the GCTB.

We generated and tested a large number of human monoclonal antibodies (mAbs) against human RON.

Representative tumor sections including adjacent precursor lesions and normal endometrium (NE) were immunostained with human monoclonal anti-COX-2.

The genes encoding broadly HIV-1-neutralizing human monoclonal antibodies (MAbs) are highly divergent from their germ line counterparts.

In this study we have generated monoclonal anti-idiotypic antibodies against human monoclonal and polyclonal anti-HIV antibodies in seropositive sera.

Taken together, these results support further development of m336 and other human monoclonal antibodies as potential therapeutics for MERS-CoV infection.

The agent is a fully- human monoclonal antibody, which binds to epidermal growth factor receptor and suppresses tumor growth, Takeda said.

Background: Ipilimumab is a human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen 4 and has shown promising activity in advanced melanoma.

We examined the in vivo efficacy of the human monoclonal antibody m336, which has high neutralizing activity against MERS-CoV in vitro.

Studies using isolation of human monoclonal antibodies followed by structural and functional characterization revealed conserved antigenic sites recognized by broadly cross-reactive antibodies.

Recently, we showed that the double reactivity of a human monoclonal RF with histones was probably due to two distinct binding sites.

The researchers created human monoclonal antibodies -immune system proteins -trained to recognize the H5N1 virus.

Methods: HLA class I-specific human monoclonal antibodies derived from women sensitized during pregnancy were tested in Luminex assays with single allele panels.

Narsoplimab is a human monoclonal antibody that targets damage to endothelial cells, which serves as a general marker of both COVID-19 and recovery.

Background: REGN3470-3471-3479 is a co-formulated cocktail of three human monoclonal antibodies targeting three non-overlapping epitopes on Ebola virus.