1
Moreover, they provide the first evidence that hTRCP1 plays a role in human neoplasia.
2
Recent studies suggest that loss of heterozygosity may play an important role in various human neoplasia.
3
Moreover, lack of faithful recapitulation of the original human neoplasia complexity is often observed in xenografted tumors.
4
Neurotrophins are growth factors which have not been shown, until recently, to be associated with human neoplasia.
5
This fact has led some investigators to postulate that fragile sites have a pathogenic role in human neoplasia.
6
Cortactin is a ubiquitous actin-binding protein that regulates various aspects of cell dynamics and is implicated in the pathogenesis of human neoplasia.
7
Aberrant DNA methylation is recognized as being a common feature of human neoplasia.CpG island hypermethylation and global genomic hypomethylation occur simultaneously in the cancer cell.
8
The activator protein-2 (AP-2) family of DNA-binding transcription factors are developmentally regulated and also play a role in human neoplasia.
9
Several different structural chromosome aberrations have been observed in human neoplasias.
10
Cytogenetic studies have revealed nonrandom involvement of some chromosomes in specific structural abnormalities in human neoplasias.
11
Derangement of the p53 tumor suppressor gene has been implicated in the aetiology of a wide range of human neoplasias.