More human Tregs may be required to suppress the stronger xenogeneic response.

In addition, this CD83 expression is also conserved on expanded human Treg.

We searched for such proteins by yeast two-hybrid assay, using GARP as a bait to screen a human Treg cDNA library.

Experimental design: To date, the most specific marker for human Tregs is demethylation in the DNA that encodes the transcription factor FOXP3.