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Praliciguat has been shown to be renoprotective in rodent models of hypertensivenephropathy and renal fibrosis.
2
Thus, these data serve as the first evidence for a direct link between Cd40 and hypertensivenephropathy.
3
Hints of a residual M1 macrophage signature were further observed in human biopsy specimens of patients with hypertensivenephropathy vs. living donor specimens.
4
Methods: Patients with both hypertensivenephropathy and diabetes type 2 and normal healthy controls were recruited from Sheikh 380 Zayed Hospital, Lahore, Pakistan.