Increasing RS to varying degrees with our newly developed system could contribute to pulsatility.

In particular, pulsatility can be shifted by delaying increased RS.

Current efforts to improve public health through increasing RS consumption could be facilitated by greater recognition of its prebiotic role.

Here, we aimed to evaluate differences between systolic assist with advanced and delayed loads by shifting the timing of increased RS.

We shifted the timing of increasing RS from -60 to +60 ms in the systolic phase.