We postulate that the mechanisms by which estradiol and progesterone induce analgesia occur through the activation of their receptor at the spinal cord level.

Baclofen induced analgesia was confirmed by means of the mouse hot plate test.

Stress- induced analgesia supports an animal's survival via prompt defensive responses against predators or competitors.

Tolerance to morphine- induced analgesia is an intractable phenomenon, often hindering its prolonged applications in the clinics.

F 13640- induced analgesia persisted during this post-treatment period.

Opioids create a neuroinflammatory response within the CNS, compromising opioid- induced analgesia and contributing to various unwanted actions.

We investigated the involvement of adenosine receptors on forced walking stress- induced analgesia using a formalin-induced paw-licking test in male mice.

Here we show that adult-stage selective ablation of orexin neurons enhances pain-related behaviors, while pharmacogenetic activation of orexin neurons induces analgesia.

The swim stress- induced analgesia was significantly decreased in neonatal morphine-exposed rats on P29, but not on P49.

The influence of calcium channel blockers on morphine- induced analgesia and on tolerance to the chronic administration of the opiate was investigated in mice.

These data indicate that morphine exposure equivalent to the third trimester of gestation produced prolonged pain hypersensitivity, decreased morphine antinociception, and decreased stress- induced analgesia.

Morphine- induced analgesia and plasma concentrations were evaluated in rats after the administration of the opiate alone or together with chlomipramine, a tricyclic antidepressant drug.

The cumulative morphine dose-response was assessed on postnatal days 20 and 49, and stress- induced analgesia was assessed on postnatal days 29 and 49.

PERSPECTIVE: A minimum of .5-hour sessions of moderate to high intensity ≥3 times a week are essential parameters for continuous and interval running-inducedanalgesia.

Exposure to forced walking stress for 6 h showed stress- induced analgesia in the second phase (10-30 min), but not in the first phase (0-10 min).