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1 Confocal microscopy showed that DMNA induced free radical generation mainly in the cytosol.
2 We show that glucose- induced free radicals increase the amounts of TRPM7 as well as total intracellular magnesium.
3 From these results, we propose that IAAUVB- induced free radicals cause human melanoma cell apoptosis via a death receptor-mediated apoptotic pathway.
4 UEGD is not dependent upon cavitation- induced free radical generation and has potential for use with a wide range of therapeutic transgenes.
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