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A severe epilepsy syndrome with triad of infantile spasms, an interictal electroencephalogram (EEG) pattern termed hypsarrhythmia, and mental retardation.
Reports on the use of topiramate for treatment of infantilespasms are limited.
2
Seizure types were variable, including infantilespasms and myoclonic seizures, and often prolonged.
3
Twelve patients had symptomatic infantilespasms, and two patients had cryptogenic infantilespasms.
4
This study evaluated the efficacy and safety of vigabatrin for Japanese patients with infantilespasms.
5
We encountered two WBS patients presenting with infantilespasms, which is extremely rare in WBS.
6
The male infant presented with tonic seizures in early infancy and subsequently developed infantilespasms.
7
Comparisons were made to recordings from infantilespasms patients.
8
Vigabatrin was deemed to be clinically effective and well tolerated in Japanese patients with infantilespasms.
9
We prospectively followed 15 children with recently diagnosed infantilespasms treated with topiramate for efficacy and tolerability.
10
Then, at about six months old, "he stopped responding and started to have infantilespasms".
11
Results: Twenty children had partial seizures; two had infantilespasms; and one had generalized tonic-clonic seizures at onset.
12
Conclusions: PLP could replace PN in the treatment of intractable childhood epilepsy, particularly in the treatment of infantilespasms.
13
The child suffered from a rare disorder called infantilespasms, which could lead to seizures, cerebral palsy and autism.
14
In patients with infantilespasms and severe developmental delay PEHO syndrome should be considered; it is not confined to Finnish heritage.
15
Recordings also revealed a ramp-up in the number of neocortical slow oscillations preceding spasms, which was also observed in infantilespasms patients.
16
Background: No large-scale studies have specifically evaluated the outcomes of infantilespasms (IS) of unknown cause, previously known as cryptogenic or idiopathic.