Binding of infected erythrocytes including field isolates to primary endothelial cells was also performed.

The natural glycosaminoglycan heparin surprisingly inhibited malaria parasite egress, trapping merozoites within infected erythrocytes.

Reduced deformability of infected erythrocytes may also contribute to disease.

Flow cytometry is a useful tool for studying phagocytic uptake of malaria- infected erythrocytes in vitro.

It was transcribed and expressed in infected erythrocytes having an apparent molecular mass of 100 kDa.

Agglutination assays detect antibodies to variant parasite antigens expressed on the surface of Plasmodium falciparum- infected erythrocytes.

In whole-cell patch-clamp analyses, biotinylation of infected erythrocytes caused significant decrease in a parasite-induced outward rectifying conductance.

The majority of infected erythrocytes in circulation are of the ring stage and these are therefore important targets to study.

To determine the enzymatic mechanism of hemoglobin degradation, we incubated trophozoite- infected erythrocytes with peptide inhibitors of different classes of proteinases.

Here, we show that these pores clearly function as an entry pathway into infected erythrocytes for compounds that inhibit parasite egress.

The investigation of phagocytosis of P. falciparum- infected erythrocytes can extend from looking solely at late-staged infected erythrocytes to include early-staged ones as well.

Affinity purified antigen-specific human antibodies and sera from P181-immunized mice recognised native proteins on malaria- infected erythrocytes in both immunofluorescence and western blot assays.

Conclusion: CF11 filtration is the most cost and time efficient method for the production of leukocyte- and platelet-free P. vivax- infected erythrocytes from field isolates.

These vesicles permit assessments of drug accumulation, pH, and membrane potential that are difficult or impossible with hematin-containing digestive vacuoles from P. falciparum- infected erythrocytes.

By killing trophozoite- infected erythrocytes, PfGARP could synergize with other vaccines that target parasite invasion of hepatocytes or the invasion of and egress from erythrocytes.

During pregnancy, Plasmodium falciparum- infected erythrocytes sequester in the placenta by adhering to chondroitin 4-sulfate, creating a risk factor for both the mother and the fetus.