1
Although both viruses infect hepatocytes, the molecular virology and cellular biology of their respective replication cycles differ.
2
IFN gamma also exhibited antiviral activity in GBV-B infected hepatocytes.
3
Culture supernatants from HIV- infected hepatocytes were capable of infecting a non-hepatic HIV indicator cell line.
4
Interestingly, treatment of GBV-B- infected hepatocytes with ribavirin resulted in an approximately 4-log decrease in viral RNA levels.
5
Antiretroviral therapy for HIV, and associated immune reconstitution, may result in immune-mediated liver damage as HBV- infected hepatocytes are targeted.
6
Our results indicated that B. abortus- infected hepatocytes have an increased MHC-I expression, but MHC-II levels remain at basal levels.
7
CD8+ T cells recognizing parasite-derived peptides on the surface of infected hepatocytes are likely the primary protective mechanism.
8
Conclusions: Hepatitis C virus nonstructural genes induce an increased expression of transforming growth factor beta1 and other profibrogenic factors in infected hepatocytes.
9
The present study was performed to determine the kinetics of disappearance of infected hepatocytes and to evaluate the role of hepatocyte turnover in this process.